Founded 1995. Still independent.
325 is a creative practice for the life sciences and the brands that fund them. Three decades. Independent. Woman-owned. Built engagement by engagement, on referral, since the year the World Wide Web went mainstream.
For nearly three decades, 325 has been the strategic force behind some of the most influential brands in biotech, healthcare, pharma, finance, and venture capital. Founded by Cheryl Marchese on the belief that great branding is both a science and an art, the studio has helped companies break through complex challenges, reimagine their purpose, and grow with impact.
We partner with mission-driven organizations that are transforming lives and industries. Using a proven, design-driven thinking methodology, 325 uncovers powerful brand narratives and brings them to life through dynamic, integrated marketing ecosystems. The work is both strategic and deeply human, designed to resonate, inspire, and deliver measurable results.
As a boutique agency with big-agency capabilities, our agile model lets us scale and flex to meet the needs of each engagement. Whether you are launching a new venture, repositioning in a saturated market, or preparing to go public, 325 is an embedded extension of your team. We collaborate with precision, creativity, and care.
We do not just build brands. We earn the right for one to be heard. In a rapidly evolving industry, companies must do more than keep up. They must connect. Our integrated solutions drive awareness, increase market share, and elevate brand equity, ensuring relevance now and in the future.
325 was founded and is led by Cheryl Marchese, Brandologist. Almost three decades building an award-winning creative practice that transforms brands in biotech, healthcare, pharma, wellness, finance, and non-profit sectors.
From a one-woman consultancy, 325 has grown into a full-service practice trusted by industry leaders, including Pfizer, Novartis, Bristol Myers Squibb, Evofem, Aspargo Labs, Buttonwood Group Advisors, Synaps DX, Angion, and Aerami Therapeutics.
Her philosophy: we already know what you need. By anticipating challenges and blending strategy with design, we create brands that resonate, inspire, and achieve results. Her approach combines creative intelligence, strategic insight, and integrated marketing expertise to unlock the full potential of clients' brands. We elevate brand awareness, position companies as market leaders, and reimagine the future of their digital presence.
Our standards.
After three decades of brand work, we have built a long list of things we will not produce on a client's behalf. Some of them are biotech-specific. The ones below are studio-wide.
- 01. Brand systems that need a brand book to be used correctly.
- 02. Logos designed by committee.
- 03. Pitch decks with seventeen shades of blue.
- 04. Discovery decks that take longer than the strategy phase they precede.
- 05. Annual reports designed for the cover, not the read.
- 06. Stock photography of hands meeting in agreement.
- 07. Voice and tone documents written in voice and tone we would not approve for clients.
- 08. Anything dressed up as strategy that is actually only design.
It's not work. It's life.
Cheryl Marchese / Founder & BrandologistBegin a conversation.
Every engagement begins with a sixty-minute call. No deck. No pitch theater. We ask about your business, your audiences, and what your last agency got wrong.